药品信息:
--------------------------------------------------------------- 部分中文Bestcall处方资料(仅供参考) ---------------------------------------------------------------
中文名称:盐酸头孢甲肟
中文别名:盐酸氨噻唑肟; 盐酸氨噻肟唑头孢菌素; 半盐酸头孢甲肟; (6R,7R)-7-(2-(2-氨基-4-噻唑基)(甲氧亚氨基)乙酰氨基)-3-(((1-甲基-1H-四唑-5-基)-硫)甲基)-8-氧代-5-硫杂-1-氮杂双环(4.2.0)辛-2-烯-2-甲酸盐酸盐
药物名称:Cefmenoxime hydrochloride, SCE-1365(free acid), Bestron, Cemix, Tacef, Bestcall
化学名:7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride; 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-
其它名称:倍司特克,Bestcall,Cefmenoxime Hemihydrochloride,盐酸氨噻肟唑头孢菌素,半盐酸头孢甲肟,Bestcall Vial,注射用盐酸头孢甲肟,Cefmenoxime Hydrochloride for Injection,立肖均,必克先安素,雷特迈星,恩诺尼
药物功效:适用于敏感菌引起的下列感染: 1.呼吸系统,如肺炎、支气管炎、支气管扩张合并感染、慢性呼吸系统疾病的继发感染、肺浓肿、脓胸等。 2.泌尿、生殖系统,如肾盂肾炎、膀胱炎、前庭大腺炎、子宫内膜炎、子宫附件炎、盆腔炎、子宫旁组织炎。 3.消化系统,如胆管炎、胆囊炎、肝脓肿、腹膜炎。 4.烧伤、手术创伤的继发感染。 5.败血症、脑脊膜炎等严重感染。
产品分类:抗感染药\抗生素\头孢菌素类\第三代头孢菌素
Pharmacology: Bestcall is a semisynthetic beta-lactam cephalosporin antibiotic with activity similar to that of cefotaxime. It has broad spectrum activity against Gram positive and Gram negative bacteria.
Additional information about Bestcall Bestcall Indication: Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria.
Mechanism Of Action: The bactericidal activity of cefmenoxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Bestcall is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Cefmenoxime
Synonyms: Cefmenoxima [INN-Spanish]; Cefmenoxime hydrochloride; Cefmenoximum [INN-Latin]
Drug Category: Anti-Bacterial Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Cefmenoxime: Cefmax; Tacef; Bestcall;
Absorption: Bioavailability is approximately 100% following intramuscular injection.
Toxicity (Overdose): Information on cefmenoxime overdosage in humans is not available. However, with other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Protein Binding: 50-70%
Biotransformation: Not appreciably metabolized.
Half Life: 1 hour
Dosage Forms of Bestcall: Powder, for solution Intramuscular Powder, for solution Intravenous
Chemical IUPAC Name: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula: C16H17N9O5S3
Organisms Affected: Enteric bacteria and other eubacteria
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2010-7-26更新 |