药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201221218144936.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文熊去氧胆酸处方资料(仅供参考)
优思佛Ursofalk 成份 活性成份:一粒胶囊含胶氧熊胆酸250mg。其化学名称为:3α,7β-二羟基-5β-胆甾烷-24-酸。 其他成份:乳浆化赋形剂
适应证 1.胆固醇性胆囊结石-结石必须是X射线能穿透的,同时胆囊收缩功能须正常; 2.胆汁返流性胃炎; 3.对于胆结石钙化病人出现胆管痉孪或胆绞痛时,不能用本品。
怀孕和哺乳期用药 由于妊娠毒性作,育龄期妇女只有在采取避孕措施期间方可接受本品治疗,为安全起见,怀孕和哺乳期妇女禁用本品。
副作用 治疗期可引起胆结石钙化,偶见稀便。
药物相互作用 本品不宜与消胆铵或含氢氧化铝的制酸剂同时合用,因可碍本品吸收。
怀孕和哺乳期用药 由于妊娠毒性作用,育龄期妇女只有在采取避孕措施期间方可接受本品治疗。为安全起见,怀孕和哺乳期妇女禁用本品。
副作用 治疗期可引起胆结石钙化,偶见稀便。
药物相互作用 本品不宜与消腥铵或含氢氧化铝的制酸剂同时合用,因可阻碍本品吸收。
用法用量 1.胆固醇性结石和固醇性肝病10mg/kg.日 2.胆汁返流性胃炎 1粒/日,晚上睡前服用 用法及疗程 按时用少量水送服: 溶石治疗 一般需6-24个月,服用12个月后结石未见变小者,停止服用,治疗结果根据每6个月进行超声波或X线检查判断。 治疗胆汗返流性胃炎 一般服用10-14天,遵从医嘱决定是否继续服药。
注意 治疗期间一定要按时服药; 服药期间应定时检查肝功能;
有效期 不能服用过期药物。 把药放在安全地方,防止儿童误服。
Generic Name: Ursodeoxycholic acid
Product Name: Ursofalk
Indication of Ursofalk: Ursofalk is used in the treatment of chronic liver disease in which the flow of bile has stopped for some reason (eg. primary biliary cirrhosis, primary sclerosing cholangitis and cystic fibrosis-related cholestasis.
Action of Ursofalk: The main ingredient of Ursofalk, ursodeoxycholic acid, is a substance that appears naturally in the body. It is used to treat cholestatic liver disease, although the mechanism is not fully understood.
Ursodeoxycholic acid alters the composition of bile, increasing concentrations of itself and decreasing amounts of toxic bile acids. It also increases bile flow.
There is some evidence that ursodeoxycholic acid may also act via an immunological mechanism, details of which are not fully understood.
Dose advice of Ursofalk: Adults and the elderly Diseases other than cystic fibrosis: •10-15mg/kg/day in two to four divided doses.
Cystic fibrosis patients: •20mg/kg/day in two to four divided doses. •Ursofalk suspension should be used in patients under 34kg.
Children •There is limited experience in children. •Doses of 15-20mg/kg/day have been used in the few available studies.
* In all patients, there may be an initial increase in symptoms, especially itching. In these cases the dose can be reduced to 1 capsule or 5ml of Ursofalk suspension daily, gradually increasing to the recommended dose.
Schedule of Ursofalk: Schedule 4
Common side effects of Ursofalk: Diarrhoea occurs in up to 3% of cases. Pruritus may be experienced at initiation of treatment.
Uncommon side effects of Ursofalk: Allergic reactions have been known to occur.
Other side effects that have been observed include: •Increased cholestasis •Nausea and vomiting •Sleep disturbance
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201221218144936.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- |